The Influence of Bisoprolol on Cariac Function and Heart Rate in Cor Pulmonale Patients with Heart Failure
- VernacularTitle:比索洛尔对慢性肺心病心力衰竭患者心功能和心率的影响
- Author:
Xi YANG
- Publication Type:Journal Article
- Keywords:
Heart failure;
Cor pulmonale;
?-receptor blocker;
Bisoprolol
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the influence of Bisoprolol on the cariac function and heart rate of in the cor pulmonale patients with heart failure. Methods 55 heart failure patients associated with cor pulmonale were randomly divided into two groups. The patients of treatment group(n=35) were orally given. The patients of control group(n=20) only received routine therapy. Bisoprolol except routing therapy. During the treatment the changes of cariac function and heart rate of all patients were observed, and before the Bisoprolol treatment and at 6th and 12th weeks after Bisoprolo treatment, the levels of creatinine, uricemia(UA), total cholesterol(TC), triglyceride(TG), high density lipoprotein cholesterol(HDL-C), and fasting plasma glucose were measured. Results In Bisoprolol treatment group the total effective rate was 94 3%, and was 75% in the control group(P0 05). Conclusion The ? 1-receptor blocker Bisoprolol was effective, and safe for treating the heart failure associated with cor pulmonale.
