An Study on the Association of Apolipoprotein E Genetypes with Cerebral infarction and Myocardial infarction in the Urumqi Old Population
- VernacularTitle:乌鲁木齐市老年人群ApoE基因与脑梗死、心肌梗死关联性研究
- Author:
Jiang HE
;
Junhao GUI
;
Wuzhong YU
- Publication Type:Journal Article
- Keywords:
Apolipoprotein E;
Cerebral infarction;
Myocardial infarction;
Genetypes;
Allele
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the association of apolipoprotein E genotype with cerebral infarction and myocardial infarction in the old population of Urumqi. Methods The polymerase chain reaction and restriction fragment length polymorphism technique were used to detect the distribution of genotype and gene frequency of ApoE alleles in 56 cases of cerebral infarction(CI), 60 cases of myocardial infarction (MI) and 104 healthy subjects as control. Results The frequency of ApoE ?3/?4 and ?4/?4 genotypes in CI and MI groups was higher than that in control group(P
