Detection of Alloiococcus Otitidis in Adults with Secretory Otitis Media
- VernacularTitle:耳炎差异球菌与成人分泌性中耳炎的相关性研究
- Author:
Xiang LIU
;
Yiqing ZHENG
- Publication Type:Journal Article
- Keywords:
Secretory otitis media;
Bacteria;
Alloiococcus otitidis;
Multiplex PCR
- From:
Journal of Audiology and Speech Pathology
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between Alloiococcus otitidis (A. otitidis) and Secretory Otitis Media (SOM) in adults.Methods The study included 39 adult patients suffering from SOM and 42 samples (middle ear effusion, MEE)were collected. We detected the four organisms(A. otitidis ,S. pneumoniae, H.influenzae and M. catarrhalis) by mutiplex PCR, for comparing the bacterial findings in the patients with or without cold history, with or without antibiotic treatment, with effusion of different characters and durations by chi-square test. Results The DNA of A. otitidis was detected from 5 MEEs(11.9%).To acute SOM, only 1 sample was PCR-positive for A. otitidis; and to chronic SOM,4 samples were positive. There was a significant difference between them. There were 3 serous MEEs and 2 mucous MEEs, which were PCR-positive for A. otitidis, and there was a significant difference between them. Antibiotic therapy didn't contribute to PCR-positive for A.otitidis. Conclusion There is A. otitidis in the MEEs of adult SOM and it may be a pathogenic factor in SOM. A. otitidis may play an important role in chronic SOM.
