Scanning Electron Microscopic Observation of the Protective effects of ?-receptor antagonist on the otoconia in the Rat
- VernacularTitle:?-受体阻滞剂对老化大鼠耳石保护作用的扫描电镜观察
- Author:
Ziming WU
;
Jianhe SUN
;
Suzhen ZHANG
- Publication Type:Journal Article
- Keywords:
receptor antagonist;
Otolith;
Scanning electron
- From:
Journal of Audiology and Speech Pathology
2004;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the protective effect of ? receptor antagonist(Vasobral) against the aging process in rats otoconia morphology.Methods 15 healthy Wistar rats were subdivided into 3 groups:Normal control( n=5 ),aging group( n=5 ) and aging plus Vasobral group( n=5 ).Results The aged otlith took the form of clew-like fusion,flattening and some giant otoconia.And there was also some sphericand strange otoconia.In the region of transitional cells,there was many otoconia phagocytosis.Some scraps of saccule lost cilia,And the otoconia in the Vasobral group appeared to be spheric and some of them adhered together,but this phenomenon was not wide-spread.No giant otoconia was found in this group.The otoconia in the transitional region was less compared with the aged group.Conclusion ? receptor antagonist(Vasobral) has the effect of protection on the aging process of the otoconia.
