Effect of Liposome Suspension on Distribution of Fluorescein Sodium in Rat Skin
- VernacularTitle:脂质体混悬液对荧光素钠在大鼠皮肤分布的影响
- Author:
Yusheng XIE
;
Yanchun XU
;
Yi HE
- Publication Type:Journal Article
- Keywords:
liposome;
fluorescein sodium;
confocal laser scanning microscope(CLSM);
bioavailability
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study effect of liposome suspension on distribution of fluorescein sodium in the rat skin.METHODS:Using0.125%fluorescein sodium(NaFl)solution as control,the distribution of NaFl in epidermis and dermis at different time periods was observed under confocal laser scanning microscope in0.125%NaFl liposome suspension group(trial group).RESULTS:The fluorescent intensity peaks in epidermis and dermis of trial group were higher than those in skin layers of control group(P
