Clinical Evaluation of Domestic Cefuroxime in the Treatment of Bacterial Lower Respiratory Tract Infec-tions
- VernacularTitle:国产头孢呋辛治疗细菌性下呼吸道感染临床评价
- Author:
Jianguo LI
;
Rui CHEN
;
Hongyu LI
;
Wei ZHANG
;
Zhiqiang LU
;
Hao WU
;
Zengshun LIAO
- Publication Type:Journal Article
- Keywords:
cefuroxime;
randomized controlled clinical trial;
bacterial infection
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the efficacy and safety of domestic cefuroxime in the treatment of bacterial lower respiratory tract infections.METHODS:A randomized controlled clinical study of cefuroxime was conducted and the results were compared with these of zinacef.The duration of treatment was7～14days in both groups.RESULTS:The overall efficacy rates were90.00%for the cefuroxime group and87.50%for the zinacef group.The bacterial clearance rates were90.91%and94.12%,the adverse drug reaction rates were7.32%and9.76%respectively.There were no statistical differences between two groups in the overall efficacy rates,the bacterial clearance rates and the adverse drug reaction rates.CONCLUSION:Domestic cefuroxime appears to be a highly effective and safe agent for the treatment of bacterial lower respiratory tract infections.
