Gas chromatographic analysis of 2,3,4,5,6-Pentafluorobenzyl monofluoroacetate
- VernacularTitle:氟乙酸五氟苄基酯的气相色谱分析
- Author:
Wenbing SHI
;
Zhenming XIE
;
Lan LIU
- Publication Type:Journal Article
- Keywords:
Forensic toxielolgy analysis;
Monofluorocetate anion ion;
2,3,4,5,6-Pentafluorobenzyl monofluoroacetate;
Gas chromatographic analysis
- From:
Chinese Journal of Forensic Medicine
2002;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine 2, 3, 4, 5, 6-pentafluorobenzyl monofluoroacetate (PFB-MFA) as the derivative of monofluoroacetate anion ion by gas chromatography, by which fluoroacetamide, one of the raticides may be analyzed. Methods The calibration curve and limit of detection were obtained by quantification of standardized PFB-MFA using GC/ECD and GC/MS. Results The linear ranges for PFB-MFA were 0.01～0.1ng/?for GC/ECD,1～100ng/?l for GC/MS SCAN and 5?10~(-3)～1 ng/?l for GC/MS SIM. The limit of detections for fluoroacetate anoin were 1.31?10~(-4)ng/?l for GC/ECD, 0.13 ng/?l for GC/MS SCAN, and 1.76?10~(-4) ng/?l for GC/MS SIM. Conclusion The monofluoroacetate anion derivative (MFAPFB) can be deterimined accurately with high sensitivity by GC/ECD and GC/MS SIM, which may be used for analysis of fluoroacetamide in forensic practice.
