Clinical impact of nonalcoholic fatty liver disease on other medical diseases.
- Author:
Jung Won YUN
1
;
Yong Kyun CHO
Author Information
1. Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Review
- Keywords:
Non-alcoholic fatty liver disease;
Cardiovascular disease;
Chronic liver disease;
Chronic kidney disease;
Metabolic syndrome
- MeSH:
Cardiovascular Diseases;
Fatty Liver;
Fatty Liver, Alcoholic;
Insulin Resistance;
Liver;
Metabolic Diseases;
Obesity;
Renal Insufficiency, Chronic
- From:Korean Journal of Medicine
2009;76(1):25-29
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Non alcoholic fatty liver disease (NAFLD) has been recognized as a hepatic manifestation of systemic metabolic disease associated with insulin resistance. Recent studies have reported that NAFLD is related with various systemic complications such as cardiovascular, renal, metabolic disease independent of obesity, other component of metabolic syndrome (MetS). Thus, NAFLD should be newly regarded as an early mediator of systemic metabolic disease as well as liver specific disease. The mechanisms of adverse effect of NAFLD on other medical diseases are not fully understood, so further study is needed for understanding and future management strategies of NAFLD.
