Progress in apoptosis,cancer and its therapy
- VernacularTitle:凋亡与肿瘤及其治疗进展
- Author:
Caihong ZHOU
;
Qifu HUANG
- Publication Type:Journal Article
- Keywords:
Apoptosis;
Mitochondria;
Death receptor;
Tumor therapy
- From:
Chinese Journal of Pathophysiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Apoptosis, a common and evolutionarily conserved property of all metazoan,is an essential part of life. The loss of cellular homeostasis balance is a character of tumor. The mitochondria (the intrinsic pathway) and the death receptors (the extrinsic pathway) are two major signal transduction pathways. With elucidation of the apoptotic molecular mechanism, some key proteins and genes related with apoptosis had been as the molecular targets for anticancer new drugs. There is the fundamental signficance to research further both apoptotic molecular mechanism and tumor therapy. [
