Recent advances in wnt-frizzled cascade and its relation to cardiovascular diseases
- VernacularTitle:Wnt-frizzled信号通路与心血管疾病关系的研究进展
- Author:
Zhilei GUO
;
Ji ZUO
;
Huiming JIN
- Publication Type:Journal Article
- Keywords:
Protein, wnt;
Receptors, frizzled;
Myocardial infarction;
Cardiovascular diseases
- From:
Chinese Journal of Pathophysiology
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Many researches have focused on the wnt-frizzled cascade in the recent years, while much work has been done in neoplastic diseases and embryology, the role of the wnt-frizzled signal transduction pathway in cardiovascular diseases has only recently begun to be explored. It plays a very important role in many physiological and pathophysiological processes, such as its transduction pathway, the healing after myocardial infarction, the proliferation, differentiation and orientation of cardiomyocytes, angiogenesis/neovascularization, cardiac hypertrophy and heart failure, the deposition of the extracellular matrix and so on. This article is aimed at its relation with myocardial infarction and the role of this pathway in cardiovascular diseases.[
