Preparation and Quality Control of Xinyoukexing Tincture
- VernacularTitle:新疣克星酊剂的制备及质量控制
- Author:
Jian CAO
;
Enjuan ZHANG
;
Linqing HUANG
;
Qin GE
;
Hua TIAN
- Publication Type:Journal Article
- Keywords:
podophyllotoxin;
Valaciclovir;
tincture;
preparation;
quality control
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the preparation technic and method of quality control of Xinyoukexing tincture(XYKX) METHODS:To determine the content of Valaciclovir by spectrophotography,and podophyllotoxin by dual-wavelength spectrophotography RESULTS:In the range of 14 88～34 72?g/ml,the Valaciclovir concentration in XYKX was in direct proportion to the absorption at 310 4nm,C=44 5 905A+1 7 556,r=0 9 998 In the range of 17 50～50 12?g/ml,the podophyllotoxin concentration in XYKX was in direct proportion to the absorption at 292nm,C=97 7 981Ap292+1 3 614,r=0 9 999,AP292=As292-As325 CONCLUSION:The preparation technic of XYKX is simple and the method of quality control is feasible
