Clincal significance of expression of vascular endothelial growth factor mRNA in human breast carcinoma tissue
- VernacularTitle:乳腺癌组织中VEGF mRNA的表达及其临床意义
- Author:
Wei WU
;
Xinsheng LU
;
Zhonghua TANG
;
Yi ZHANG
;
Xiaorong LI
;
Daoji CHEN
- Publication Type:Journal Article
- Keywords:
BREAST NEOPLASMS/genet;
VASCULAR ENDOTHELIAL GROWTH FACTOR;
GENE EXPRESSION
- From:
Chinese Journal of General Surgery
2000;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). The expression of VEGF121 mRNA and VEGF165mRNA in BC with lymph node metastasis was significantly higher than that in BC without lymph node metastasis(P=0.033,0.004).Conclusions The expression of VEGF121 mRNA and VEGF165mRNA in BC tissues is upregulated, and VEGF121mRNA is likely to play the major role. A high level expression of VEGF mRNA in BC patient indicates the likelihood of lymph node metastasis.