Effect of Polygona-polysaccharose on Expression of RAGE mRNA in Brain of Diabetic Rats
- VernacularTitle:黄精多糖对糖尿病鼠脑组织糖基化终产物受体mRNA表达的影响
- Author:
Shenrong WU
- Publication Type:Journal Article
- Keywords:
polygona-polysaccharose;
diabetic rat model;
receptor for advanced glycation endproducts(RAGE)mRNA
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE:To study the regulative function of polygona-polysaccharose on the expression of RAGE mRNA in diabetic rats’brain.METHODS:Diabetic rat model was made by intraperitoneal injection of streptozotocin.RT-PCR method was used to examine the expression of RAGE mRNA in rats’brain.RESULTS:The expression of RAGE mRNA in brain tissue of diabetic rats was increased.The value of RAGE/?-actin in diabetic rats was significantly higher than that in the control group(P
