Association of serum soluble E-selectin concentrations with insulin resistance in essential hypertension patients
- VernacularTitle:原发性高血压患者血清可溶性E选择素水平与胰岛素抵抗的关系
- Author:
Jianriang ZHANG
;
Yongwen QIN
;
Xing ZHENG
;
Jianli QIU
;
Lezhi ZHANG
;
Jianrong ZHANG
;
Dajin ZOU
- Publication Type:Journal Article
- Keywords:
E-selectin;
Insulin resistance;
Hypertension
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the relationship between serum soluble E-selectin (sE-selectin) and insulin resistance, serum uric acid, serum lipid in essential hypertension patients. METHODS: Fasting serum sE-selectin concentration, plasma glucose, serum insulin, serum uric acid, total cholesterol, triglycerides, high density lipoprotein-cholesterol, low density lipoprotein-cholesterol were determined in 186 patients with essential hypertension (75 males, 111 females). Homeostasis model assessment was applied to assess the status of insulin resistance (HOMA-IR). RESULTS: Based on the HOMA-IR, the essential hypertension patients were divided into insulin-sensitive individuals (IS) and insulin resistant subjects (IR). The serum sE-selectin concentration was significantly higher in male group [(50.1?17.8)?g/L] than in female group [(40.6?16.6)?g/L] (P
