Angiopoietin-1 and regulation of vascular permeability
- VernacularTitle:促血管生成素-1与血管通透性调节
- Author:
Fei YUE
;
Huiming JIN
- Publication Type:Journal Article
- Keywords:
Angiopoietin;
Endothelial cells;
Capillary permeability
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Angiopoietin-1 (Ang-1) is a newly-found endothelium-specific proangiogenic factor and it had been proved essential roles in both vasculogenesis and angiogensis. Among them, its anti-leakage ability may have great potential applications in clinical treatment of vascular hyper-permeability in a variety of diseases such as cancer, diabetic retinopathy, rheumatoid arthritis, asthma. In this review, some research progresses focused on this aspect are discussed. [