Progresses on antitumor effect of snake venom active components
- VernacularTitle:蛇毒的抗肿瘤活性成分研究进展
- Author:
Xiaohong LI
;
Shaohui CAI
;
Xianda REN
- Publication Type:Journal Article
- Keywords:
Snake venoms;
Adhesions;
Angiogenesis, pathologic;
Apoptosis;
Neoplasms
- From:
Chinese Journal of Pathophysiology
2000;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Many snake venoms contain complex mixtures of pharmacologically important molecules, some of which show potential therapeutic value in the treatment of cancer and other human disorders. In this review, we mainly reports the effects of snake venom active components, such as disintegrins and lectins in paralyzing cancer cells, blocking on cell migration, interaction with integrins, inhibition of tumor dissemination and angiogenesis. The advanced researches on the snake venom's apoptosis-inducing components on tumors are also introduced. [
