Preliminary study on pathogenesis of achalasia
- VernacularTitle:贲门失弛缓症发病机制的初步探讨
- Author:
Enbin XU
;
Zhongbing ZHANG
;
Lei ZHANG
- Publication Type:Journal Article
- Keywords:
Achalasia,esopheal;
Acetylcholinesterase
- From:
Chinese Journal of Digestive Endoscopy
1996;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To elucidate the pathogenesis of achalasia, Benzyldimethyltetradecylammo-nium chloride ( BAC) was used to create amyenteric cat achalasia models. Methods Twenty-four cats were randomized into two groups and injected respectively with BAC in models or saline in controls into the distal esophagus under endoscopy. After 8 weeks, manometry, biopsy with HE stain, acetylcholinesterase activity and immunohistochemistry were studied. Results Manometrically, the pressures of LES in cat models showed higher than those of the controls (P
