Comparative study of the effects of pancreas transplantation models using enteric drainage and bladder drainage reconstruction methods in rats
- VernacularTitle:大鼠胰肠和胰膀胱重建式单纯胰腺移植模型的比较研究
- Author:
Xiaonan LIU
;
Weizhong WANG
;
Kaizong LI
;
Wenxian GUAN
;
Caiping CHEN
;
Dongli CHEN
- Publication Type:Journal Article
- Keywords:
PANCREAS TRANSPLANTATION;
PANCREATO ENTERIC DRAINAGE RECONSTRUCTION;
PANCREATO BLADDER DRAINAGE RECONSTRUCTION;
BLOOD VESSEL ANASTOMOSIS
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of pancreatic transplantion(PTA) using diverse operative (methods) in rats. Method Inbred SD rats were used as donor and recipient, and were randomly assigned (into) 4 groups:Normal control group( Group NC), consisted of 10 rats;diabetes group(Group DC) consisted of 10 rats;PTA with enteric drainage group(Group E-D), consisted of 22 diabetic rats;PTA using bladder reconstruction group(group B-D), consisted of 22 rats.Arterial supply of transplanted pancreas was (performed) by using end-to-side anastomosis of the donors' abdominal aorta(with splenic artery) and (recipients)′ abdominal aorta; and venous drainage was performed by using end-to-end anastomosis of the (donors)' portal vein segment(with splenic vein) and (recipients)′ left renal vein(cuff method). The fasting blood glucose, body weight, food intake, water intake and urine volume of the recipient were monitored before transplantation and on the 1st, 3rd, 7th, 14th, 30th day after operation, and also the reasons of failures were analyzed. Results The operative time of recipient in E-D group was significantly longer than that in B-D group(P
