Evaluation of N-Terminal Pro Brain Natriuretic Peptide for Assessment of Left Ventricular Remodeling and Left Ventricular Function in Acute Myocardial Infarction
- VernacularTitle:氮末端脑钠素前体评价急性心肌梗死后左心室功能及重构
- Author:
You ZHONG
;
Xinheng FENG
- Publication Type:Journal Article
- Keywords:
Brain natriuretic peptide;
Myocardial infarction;
Left ventricular remodeling
- From:
Chinese Circulation Journal
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the value of N terminal pro brain natriuretic peptide(NT proBNP) in assessment of left ventricular remodeling and left ventricular function in patients with acute myocardial infarction. Methods:Echocardiography was performed in 61 patients with acute myocardial infarction(AMI) and in 20 control participants Plasma samples for NT proBNP were obtained at 48 96 hours after AMI.NT proBNP was determined by ELISA method. Results:Compared with controls NT proBNP in AMI patients were significantly higher ( p 55.The sensitivity,specificity and accuracy were 84 6%,65 5% and 77 7%,respectively.In Multivariate analysis NT proBNP was correlated with Killip classification and wall motion index. Conclusion:Plasma NT proBNP was significantly increased in AMI patients Plasma NT proBNP was correlated with cardiac functional class and extension of myocardial infraction.
