The Corelation of Mucosal Involvement and Corticosteroid Dosage in Bullous Pemphigoid
- VernacularTitle:大疱性类天疱疮患者黏膜受累与糖皮质激素控制量的相关性
- Author:
Jianbing WU
;
Pangen CUI
;
Yanxia YUAN
;
Lin LIN
;
Yuanhua CAO
- Publication Type:Journal Article
- Keywords:
Pemphigoid, bullous;
Mucosa membrane;
Corticosteroids
- From:
Chinese Journal of Dermatology
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the corelation of mucosal involvement and corticosteroid dosage in the control of bullous pemphigoid(BP). Methods One hundred and three in-patients with bullous pemphigoid hospitalized during 1988 - 2002 were retrospectively analyzed for their mean corticosteroid dosage for controlling the disease and the duration for complete relieving the skin lesions, as well as the duration to start corticosteroid tapering. All the patients were divided into two groups: group A (37 cases) with mucosal involvement and group B (66 cases) without mucosal involvement. Results The mean corticosteroid dosage used to control the disease in group A was much higher than that in group B (t = 3.488, P 0.05). Conclusion Patients with mucosal involvement require a higher dosage of corticosteroids to control the disease.