Effects of Ganlan Jiejiu Yin on ALT and AST in Rats and Mice with Acute Alcoholic Hepatic Injury
- VernacularTitle:橄榄解酒饮对急性酒精性肝损伤大鼠、小鼠丙氨酸转氨酶、天冬氨酸转氨酶的影响
- Author:
Bo PENG
- Publication Type:Journal Article
- Keywords:
@Ganlan Jiejiu Yin;
Hepatic diseases, alcoholic/blood
- From:Journal of Traditional Chinese Medicine
1993;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe preventive and therapeutic effects of Ganlan Jiejiu Yin on acute alcoholic hepatic injury in the rat and the mouse, and to study preliminarily effects on alinine transaminase(ALT) and aspartic transaminase (AST) in serum and hepatic homogenate. Methods: The acute alcoholic hepatic injury model was made by stomach perfusion of white spirit for 5 days, and drunk time and the recovering time were observed every day, and serum ALT on the 3rd day and ALT and AST in serum and hepatic homogenate on the 5th day were determined, and the results were compared with those of Hugan Capsules. Results: Ganlan Jiejiu Yin could significantly decrease the drunk rate, increase the recovery/drunk ratio, and decrease ALT and AST in serum and ALT in hepatic homogenate with significant differences as compared with those of the control group. Conclusion: Ganlan Jiejiu Yin has good drunk-preventing, alcoholism-relieving and liver-protecting actions.
