Effect of Ulinastatin on Serum Amylase(AMS)and Tumor Necrosis Factor-?(TNF-?)in Acute Necrotic Pancreatitis in Rats
- VernacularTitle:乌司他丁对急性坏死性胰腺炎模型大鼠血清淀粉酶、肿瘤坏死因子的影响
- Author:
Yali WU
;
Yan HAI
;
Bingzhang TIAN
- Publication Type:Journal Article
- Keywords:
acute necrotic pancreatitis;
Ulinastatin;
TNF;
serum amylase
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the pharmacological effect of Ulinastatin on acute necrotizing pancreatitis in rats.METHODS:Animal models were divided into3groups:group A,sham operation;group B,acute necrotic pancreatitis given no treatment;group C,acute necrotic pancreatitis treated with Ulinastatin.The changes of AMS and TNF-?were compared at different time among3groups.RESULTS:AMS and TNF-?in group C were significantly different from those in group A and in group B.CONCLUSION:Ulinastatin could remarkably improve the prognosis of acute necrotic pancreatitis.
