Systematic and Quantitative Analysis of ADRs of Oral Penicillins
- VernacularTitle:青霉素类口服制剂不良反应系统性定量分析
- Author:
Shiping FANG
;
Zhenyu PAN
- Publication Type:Journal Article
- Keywords:
oral Penicillins;
ADRs;
systematic and quantitative analysis;
pharmacoepdemiology
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To find out the regulareity of adverse reactions(ADRs)induced by oral Penicillins(QMSK)and evaluate the safety of QMSK in clinical use.METHODS:Data of ADRs of QMSK,which collected from published articles were retrieved from CHINESE PHARMACEUTICAL ABSTRACT issued between January1995and April2003.According to the given standard,the data were statistically analysed.RESULTS:There were334cases which had24kinds of ADRs of QMSK,of which,121cases were male while213cases were female.There were drug eruption in249cases(74.55%),allergic shock34(10.18%),exfoliative dermatitis9(2.7%)and toxic epidermalnecrolysis7(2.1%),miscellaneous reactions31(8.97%)and5(1.5%)deaths.CONCLUSION:QMSK caused ADRs apparently.QMSK should be used according to penicillins for injections and safe of patients should be ensured in use of QMSK.
