Determination of the Content of Baicalin in Bifukang Oral Liquid by HPLC
- VernacularTitle:高效液相色谱法测定鼻复康口服液中黄芩苷的含量
- Author:
Xiaoyong SONG
;
Lei WEI
- Publication Type:Journal Article
- Keywords:
HPLC;
baicalin;
content determination
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a HPLC method for determination of the content of baicalin in Bifukang oral liq?uid.METHODS:The ODS C 18 column was used with methanol-water-glacial acetic acid(45∶55∶1.5)as mobile phase,and de?tective wavelength was274nm,the flow rate was1ml/min.RESULTS:Within the range of0.215?g~4.3?g,baicalin presented a fine linear relationship between amount and peak area(r=0.9995).The average recovery was99.44%(RSD=0.79%,n=5). CONCLUSION:This HPLC method is convenient,rapid and accurate,and can be used for quality control in the production of Bifukang oral liquid.