Relation between TNF-?,TNFR I expression and apoptosis in oral lichen planus
- VernacularTitle:口腔扁平苔藓中肿瘤坏死因子?和肿瘤坏死因子受体I表达及与细胞凋亡的关系
- Author:
Lijia SHEN
;
Ping RUAN
;
Cao YIN
;
Siming XIE
;
Ton ZHAO
- Publication Type:Journal Article
- Keywords:
Lichen planus, oral;
Tumor necrosis factor;
Receptors, tumor necrosis factor;
Apoptosis
- From:
Chinese Journal of Pathophysiology
1999;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To examine the expression and distribution of tumor necrosis factor-? (TNF-?), tumor necrosis factor receptor I (TNFR I) and apoptosis in oral lichen planus, and evaluate their roles and relation in the oral lichen. METHODS: Immunohistochemical technique and TUNEL were employed to study the expression of TNF-?, TNFR I and apoptosis in 50 cases of oral lichen planus and 10 normal oral mucosa specimens. RESULTS: Compared with the normal control group, TNF-? expression was upregulated in mononuclear cells in lamina propria and decreased in keratinocytes in oral lichen planus lesion ( P
