The Effect of Troglitazone on the High Glucose-induced mPGEs Expression in Rat Mesangial Cells
- VernacularTitle:PPAR-?激动剂Troglitazone对高糖诱导的大鼠肾小球系膜细胞mPGEs蛋白表达的影响
- Author:
Guanghui LING
;
Youming PENG
;
Haitao WANG
- Publication Type:Journal Article
- Keywords:
mPGEs;
PPAR-?;
Glucose;
Mesangial cell
- From:
Journal of Chinese Physician
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of PPAR-r agonist Troglitazone on the mPGEs expression induced by high glucose in rat mesangial cells. Methods Rat mesangial cells were incubated with high glucose at presence or absence of different concentrations of Troglitanzone, and the mPGEs concentration in supernatant was measured by an enzyme-linked immunosorbent assay (ELISA). Results 5% glucose could obviously induce the mPGEs expression in the rat mesangial cells (P
