A Study on the Expression and Correlation of GST-? and p53 in Human Lung Cancer
- VernacularTitle:肺癌组织中GST-?和p53的表达及其相关性研究
- Author:
Xiangyu CHI
;
Shujuan JIANG
;
Jianqiang SHANG
- Publication Type:Journal Article
- Keywords:
Lung carcinoma;
Glutathione-s-transferase;
p53 protein;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical pathological significance and relationship of placental glutathione-s-transferase(GST-?) and p53 protein expression in the tissues of human lung carcinomas. Methods The expressions of GST-? and p53 in 60 cases of lung carcinomas were detected by the LSAB immunohistochemical method. Results The positive rates of GST-? and p53 protein expression in lung carcinomas were 56 67% and 31 67% respectively. The expressions of both GST-? and p53 had obvious relationship with the differential degree of the tumors(P
