Multi-factor analysis of the effects on visual acuity prognosis of photodynamic therapy for choroidal neovascularization
- VernacularTitle:影响光动力疗法治疗脉络膜新生血管视力预后的多因素分析
- Author:
Li ZHANG
;
Mingwei ZHAO
;
Xiaoxin LI
- Publication Type:Journal Article
- Keywords:
Choroidal neovascularization;
Phototherapy;
Multivariate analysis
- From:
Chinese Journal of Ocular Fundus Diseases
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related factors of effects on distant visual acuity after photodynamic therapy (PDT) for choroidal neovascularization (CNV). Methods One hundred and thirty-five cases (135 eyes) of CNV treated with PDT were observed. The gender, preoperative distant and near visual acuity, disease course, pathogeny, area of CNV, types of CNV ascertained by fundus fluorescein angiography (FFA), and changes of CNV in FFA were recorded. Multi-factor regression analysis of visual acuity within 1 month and 3 months after PDT was performed with SPSS statistics software. Results The distant visual acuity within 1 month postoperatively was related to the preoperative distant visual acuity, the area of CNV and the changes in the FFA(P=0.000,0.030,0.062), and 3 months after PDT, it was related to the distant and near visual acuity preoperatively and the changes in the FFA(P=0.000,0.054,0.034). The condition of distant visual acuity within 1 month postoperatively was related to the FFA type of CNV and the disease course(P =0.018,0.08). Conclusion The smaller the area of CNV is, the better postoperative distant visual acuity would be. The proportion of improvement of visual acuity is relatively higher in patients with classic CNV. Early treatment for the patients with the indicatio may improve the visual acuity effectively.
