Optimization of Base Composition and Technology for5F Scar Emulsion by Orthogonal Design
- VernacularTitle:正交设计法优选5F疤痕乳膏基质组成及制备工艺
- Author:
Kefeng WU
;
Nan TANG
;
Baohong LI
- Publication Type:Journal Article
- Keywords:
orthogonal design method;
5F scar emulsion;
base material;
technology
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimizate base material composition and technology for5F scar emulsion.METHODS:According to the factors that affect the stability of emulsion,orthogonal design method L 9 (3 4 )was used,glyceryl monostearate,triethanolamine,sodium lauryl sulfate and emulsifying temperature were selected as variable factors.RESULTS:The optimum base material composition and technology were glyceryl monostearate6%,sodium lauryl sulfate0%,triethanolamine0.5%,emulsifying temperature80℃.CONCLUSION:The5F scar emulsion prepared by this composition and technology accords with the stipulation of Chinese Pharmacopoeia(2000).