Effects of Round Window Membrane Rupture on Morphological Changes of Guinea Pig's Cochlea
- VernacularTitle:豚鼠圆窗膜破裂引起耳蜗形态变化的探讨
- Author:
Xiuli LIU
;
Xu BIE
- Publication Type:Journal Article
- Keywords:
Perilymphatic fistula;
Cochlea;
Morphological;
Guinea pig
- From:
Journal of Audiology and Speech Pathology
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Clinical reports on perilymphatic fistulae(PLF) of the round window membrane(RWM) have shown different degrees of hearing loss. For the unknown mechanisms of hearing loss, the morphological changes of cochlea with perilymphatic fistulae(PLF) was studied.Methods Among 10 guinea pigs, each ear on one side was punctured and the ear of another side was used as control. 4 hours after operation, the morphological changes of cochlea were observed.Results It was found that 2 ears with endolymphatic hydrops, 1 ear with strica vascularis stripped, venous hyperemia and hemorrhage in cochlea, 7 ears with no changes.Conclusion The study suggestes that the normal and the abnormal morphological changes of cochlea can all be seen after the rupture of RWM.