A case of microinvasive Paget's disease of the vulva: Treatment of positive resection margin with topical 5-FU cream application.
- Author:
Ho Jeong KANG
1
;
Chul Min PARK
;
Soon Sup SHIM
;
Young Soo SON
;
Sung Yob KIM
Author Information
1. Department of Obstetrics and Gynecology, Cheju National University, College of Medicine, Jeju, Korea. kimsy@cheju.ac.kr
- Publication Type:Case Report
- Keywords:
Extramammary Paget's disease of the vulva;
5-fluorouracil (5-FU)
- MeSH:
Biopsy;
Fluorouracil;
Follow-Up Studies;
Recurrence;
Vulva;
Vulvar Neoplasms
- From:Korean Journal of Obstetrics and Gynecology
2009;52(3):372-376
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Extramammary Paget's disease of the vulva is a rare lesion that accounts for 1~2% of vulvar neoplasms. Paget's disease often has a microscopic extension beyond the gross lesion and shows a multifocal distribution. Positive resection margin is common. We applied 5-FU cream on the lesion who had a positive resection margin. There was no residual lesion on multiple punch biopsies after 5-FU cream treatment three months later. And there has been no evidence of disease recurrence in the 12-month follow-up period. We experienced a case of effective treatment with 5-FU cream in microinvasive Paget's disease of the vulva with positive resection margin. We present it with a brief review of literatures.
