Advances in the research of the tumor suppressor gene-PTEN in head and neck squamous cell carcinomas
- VernacularTitle:头颈部鳞癌中抑癌基因PTEN的研究进展
- Author:
Siming XIE
;
Lijia SHEN
- Publication Type:Journal Article
- Keywords:
Genes, tumor suppressor gene;
Head and neck neoplasms
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
The PTEN, having a dual specificity phosphatase activity, is the first tumor suppressor gene that possess phosphatase activity hitherto. Many researches have suggested that PTEN play a major role in the tumorgenesis. In clinical, the head and neck squamous cell carcinoma(HNSCC) is one of the most common malignant tumors. In this review, advances in the research of PTEN and the relationship between the PTEN and HNSCC are discussed.
