An immunohistochemical study on relationship between the changes of actin in cardiac and skeletal muscle cells and postmortem interval in rats
- VernacularTitle:大鼠死后心肌骨骼肌细胞肌动蛋白变化及与死亡时间的关系
- Author:
Jiangming LU
;
Jiashu YU
;
Minjing CHEN
- Publication Type:Journal Article
- Keywords:
Forensic pathology;
Cardiac muscle;
Skeletal muscle;
Actin;
Immunohistochemistry;
Postmortem interval
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the changes of actin in cardiac muscle and skeletal myogen cells and postmortem interval in rats.Methods The changes of actin in cardiac muscle and skeletal myogen cells at different postmortem intervals were observed by immunohistochemical S-P method using anti-actin monoclonal antibody (HHF35)and analyzed by IBSA image analysis system.Results Within 54h postmortem,cardiac and skeletal muscles revealed depletion of HHF35 staining.The extent of HHF35-staining depletion increased with extension of postmortem interval.Statistical difference was significant in the data obtained by IBSA image analysis system (F cardiac muscle =588.27,F skeletal muscle =351.25,P
