A Clinical Study on the Level of Lymphocyte Sub-population and NK Cell in Patients with Primary Lung Malignant Tumor and COPD Patients
- VernacularTitle:原发性肺部恶性肿瘤与COPD患者外周血淋巴细胞亚群和NK细胞水平测定的临床探讨
- Author:
Jinwei XIA
;
Beiyun WANG
;
Yiwen LIU
- Publication Type:Journal Article
- Keywords:
Lymphocyte sub-population;
Primary lung malignant tumor;
Chronic obstructive pulmonary disease(COPD)
- From:
Journal of Chinese Physician
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of lymphocyte sub-population and NK levels in patients with primary lung malignant tumor and patients with chronic obstructive pulmonary disease (COPD). Methods The percentage of CD3 +,CD4 +, CD8 +, CD19 + and NK cells were measured in 60 COPD patients and 50 primary lung malignant tumor patients and 40 normal control subjects using alkaline phosphatase antialkaline phosphatase (APAAP) assay, and CD4 +/CD8 + ratio was calculated. Results The levels of CD3 +,CD4 +,CD4 +/CD8 + and CD19 + cells were significantly lower in the patients with primary lung malignant tumor or COPD than those in the normal control subjects, which CD8 level was significantly higher (P0.05). No difference in the levels of CD3 +, CD4 + and CD8 + cells was found between the primary lung malignant tumor and COPD patients, but NK and CD19 + cells levels had significant difference(P
