Application of the number of alleles identical by state in full sib test
- VernacularTitle:共有基因数在同胞鉴定中应用的研究
- Author:
Jing WANG
;
Yacheng LIU
;
Hui TANG
- Publication Type:Journal Article
- Keywords:
Forensic biological evidence;
Alleles identical by state;
Discriminant analysis;
Posterior probability;
STR
- From:
Chinese Journal of Forensic Medicine
1988;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Establish and evaluate the method of number of alleles identical by state in full sib test.Methods Sib pair group and unrelated individual pair group were genotyped in 13 STR loci,statistical calculation was carried out.Results Through analysis by discriminant function the posterior probability of membership in each group and error of the posterior probability was obtained.The discriminant function in sib group is L sib =-27.087 03+3.202 32S(S:number of alleles identical by state);The discriminant function in unrelated individual group is:L unrelated =-7.495 63+1.685 09S.The average error of the posterior probability in sib and unrelated pair group is 0.026 5.Conclusion When the number of alleles identical by state is more than 17 or less than 8,posterior probability of a full sib or unrelated individuals is more than 0.998 0 or 0.999 4,respectively.The method based on the number of alleles identical by state in full sib test is credible in identifying sib pair relationship.
