The establishment of a nude mouse model of intrahepatic implantation of human liver carcinoma tissue with unchanged tumor biologic features
- VernacularTitle:保持人肝癌生物学特性的人肝癌组织裸鼠肝内种植模型的建立
- Author:
Yongshun GAO
;
Xiaoping CHEN
;
Kaiyan LI
;
Zaide WU
- Publication Type:Journal Article
- Keywords:
Carcinoma,hepatocellular;
Neoplasm seeding;
Nude mouse;
Metastasis
- From:
Chinese Journal of General Surgery
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Second and third generation of the implanted tumor were obtained in 8 nude mice respectively,and all transplanted tumors survived. Liver,bone and lung metastasis were found in 100% of nude mice between 10 w~14 w. [WT5”HZ] Conclusions This nude mouse HCC model holds the biologic features of human HCC and serves the purpose of in vivo study investigation .