Effect of Hyphal and Conidial form on the in vitro Antifungal Susceptibility Testing of Some Filamentous Fungi to Terbinafine
- VernacularTitle:特比萘芬体外抗丝状真菌药物敏感试验:菌体不同形态对MIC的影响
- Author:
Jingsi ZENG
;
Yuechen ZHENG
;
Yanqing WU
;
Zhijian TAN
;
Xin LIAN
- Publication Type:Journal Article
- Keywords:
Antibiotics, antifungal;
Microbial sensitivity tests;
Fungi;
Hyphae;
Spores, fungal
- From:
Chinese Journal of Dermatology
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
16 ?g/mL, and ≤0.03 ?g/mL , respectively. The MICs did not show significant differences among the ungerminated conidia and the germinated conidia for all the isolates tested except A.versicolor and Phialophora verrucosa. Conclusions Terbinafine is effective against the isolates of Aspergillus spp., dematiaceous fungi and dermatophytes in vitro except Pseudallescheria boydii and Scedosporium apiospermum. The MIC of terbinafine obtained with ungerminated conidia may reflect the antifungal activity of terbinafine against germinated conidia and hyphae of some filamentous fungi in vitro.
