Analysis of the Clinical Characteristics and Related Factors in Occurrence of ADRs of Chinese Prepared Medicines
- VernacularTitle:中成药药物不良反应的临床特征及发生的相关因素分析
- Author:
Mei GUAN
;
Zelian CHEN
;
Xiaoou PAN
;
Yao TANG
- Publication Type:Journal Article
- Keywords:
Chinese prepared medicines;
ADR;
clinical characteristic;
related factor
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To analyze the ADRs caused by Chinese prepared medicines.METHODS:638ADRs were col?lected from medical journals of2001～2002in consideration of sex,age,administration route,the time of the occurrence and clinical manifestations.RESULTS:There were638ADR cases involving76kinds of Chinese prepared medicines reported in256articles.Of them,shuanghuanglian injection was the most common preparation(87cases).The commonest clinical manifesta?tions were allergic reactions(157cases),followed with the liver and kidney injury.The ages of patients were mostly above60years,the time of the occurrence was mostly within30minutes after administration and about92%of the patients recovered within24hours.CONCLUSION:The occurrence of ADRs of Chinese prepared medicines is related to the route of administra?tion,dosage form of drug,quality of drug,patient’s age and constitution.
