The role of intestinal fatty acid-binding protein as a marker in the early diagnosis of intestinal ischemia
- VernacularTitle:肠型脂肪酸结合蛋白对肠缺血早期诊断的意义
- Author:
Haidong ZHAO
;
Xiaofeng TIAN
- Publication Type:Journal Article
- Keywords:
MESENTERIC VASCULAR OCCLUSION/diag;
FATTY ACID-BINDING PROTEIN/blood
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of intestinal fatty acid-binding protein(IFABP) as a marker in the (early) diagnosis of intestinal ischemia. Methods SD rats were randomly divided into control group and superior mesenteric artery ligation group (SMA group). Blood samples were collected sequentially at pre-operation, 1, 2 and 4 hours after operation for detecting the activity of IFABP, CK, CK-BB and LDH. Results The activity of IFABP in SMA group elevated 1h and arrived to a peak at 2 hours postoperatively. Compared with control group, all the (levels) of CK, CK-BB and LDH in SMA group were elevated progressively with time after operation. Compared with control group, the significant elevation was at 1, 2 and 4 hours after opration. Conclusions I-FABP is a sensitive and specific marker in the diagnosis of intestinal ischemia.
