Detection of the expression of hTERT mRNA and telomerase activity of pancreatic juice in the diagnosis of pancreatic cancer
- VernacularTitle:胰液中端粒酶及亚单位检测对胰腺癌的诊断价值
- Author:
Tao LIU
;
Chunyou WANG
;
Chidan WAN
;
Jiongxin XIONG
;
Kailin CAI
- Publication Type:Journal Article
- Keywords:
PANCREATIC NEOPLASMS/diag;
TELOMERASE;
PANCREATIC JUICE
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study and evaluate the diagnostic and differencial diagnostic value of detection of human telomerase reverse transcriptase(hTERT) mRNA and telomerase activity in pancreatic juice of (pancreatic) cancer(PC) .Methods hTERT mRNA expression and telomerase activity in pancreatic juice in 24 cases of (pancreatic) cancer and 14 cases of chronic pancreatitis(CP) were detected and compared.Results Expression of hTERT mRNA was detected in 87 .5% (21/24) of PC cases and 21.4%(3/14) of CP cases(P
