Structure, function and signal transduction of vascular endothelial growth factor receptor-2
- VernacularTitle:血管内皮生长因子受体2的结构功能与信号转导
- Author:
Jiyan LIU
;
Yuquan WEI
- Publication Type:Journal Article
- Keywords:
Angiogensis, pathologic;
Receptors, vascular endothelial growth factor;
Signal transduction
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Angiogenesis, or the formation of new blood vessels out of pre-existing capillaries, is very important in many physiologic and pathologic processes, such as embryonic development, cancer, retinopathies, etc. Vascular endothelial growth factor receptor-2 (VEGFR-2) plays a key role in angiogenesis. In this review, we discussed the structure, function and signal transduction of vascular endothelial growth factor receptor-2. Understanding these should provide important insights into how new strategies can be devised to interfere in the physiologic and pathologic processes involved in angiogensis. [
