The Expression of IL-8 mRNA, TSP-1 mRNA and Their Clinicopathologic Value in the Breast Cancer
- VernacularTitle:乳腺癌IL-8 mRNA和TSP-1 mRNA检测及临床病理意义
- Author:
Shugen LI
;
Xingming YIN
;
Yanchun LI
- Publication Type:Journal Article
- Keywords:
Mammary neoplasmas;
Cytokines;
Messenger RNA;
In situ hybridization
- From:
Journal of Chinese Physician
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions of IL-8 mRNA, TSP-1 mRNA and their clinicopathologic significance in the breast cancer. Methods The expressions of IL-8 mRNA, TSP-1mRNA were detected by in situ hybridization technique on the 10% formalin-fixed and routinely paraffin-embedded sections of 58 breast cancer tissues and 15 lobular hyperplastic tissues of mammary gland. Results The positive rate of IL-8mRNA was significantly higher in the breast cancer than that of lobular hyperplasia (56 9% vs 13 3%,P