Influence of Sodium Nitroprusside on Cell Motility of Outer Hair Cells of Guinea Pigs
- VernacularTitle:硝普钠对豚鼠耳蜗外毛细胞能动性影响的初步研究
- Author:
Jianbo ZHOU
;
Weijia KONG
- Publication Type:Journal Article
- Keywords:
Sodium nitroprusside;
Outer hair cells;
Patch clamp whole cell recording;
L-type calcium channels;
Cell motility
- From:
Journal of Audiology and Speech Pathology
1998;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes of cell motility of outer hair cells in the cochlear of guinea pigs under treatment of sodium nitroprusside(SNP). Methods By using the whole cell patch clamp recording technique in normal external and internal cell solution, the cell motility of outer hair cells under stimulation of voltage was observed in different concentration of SNP. Results Sodium nitroprusside apparently inhibited outer hair cells' motility when SNP concentration was higher than 100 ?Mol/L ( P
