Studies on Immunosuppressive Anthraquinone Constituents from Tripterygium wilfordii hook.f
- VernacularTitle:雷公藤免疫抑制成分蒽醌的研究
- Author:
Chunxin YANG
;
Ying DONG
;
Ainiu MA
;
Xiaoliang TONG
- Publication Type:Journal Article
- Keywords:
Tripterygium wilfordii hook.f.;
anthraquinone;
emodin;
immunosuppression
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the immunosuppressive chemical constituents from the n-butanol extract of the debark root of Tripterygium wilfordii hook.f.METHODS:Several compounds were isolated from the n-butanol extract by columns of silica gels and Sephadex LH-20,their structures were identified by NMR,MS spectral analysis and comparing with standard substances on TLC,and the immunosuppressive activity was determined.RESULTS:One of the compounds was identified as emodin,an anthraquinone,it had marked immunosuppressive effect on animal.CONCLUSION:Emodin is obtained from the plants of Tripterygium wilfordii hook.f.for the first time.
