Influence of acute-hypervolemic-hemodilution with 6% medium-molecular weight hydroxycthyl starch on renal function
- VernacularTitle:6%羟乙基淀粉急性超容性血液稀释对开胸手术患者围术期肾功能的影响
- Author:
Guoqing ZHANG
;
Yue LI
;
Yicong LI
- Publication Type:Journal Article
- Keywords:
Hetastarch;
Hemodilution;
Kidney function tests
- From:
Chinese Journal of Anesthesiology
1994;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
65 mm Hg and CVP between 10-14 cm H2O. In control group no AHHD was performed. Blood samples and urine specimens were obtained before anesthesia (T1), at the end of operation (T2 ) and 72 h after operation (T3 ) for determination of blood and urinary creatinine (BCr, UCr) , blood sodium (BNa) , urinary sodium (UNa), blood urea nitrogen (BUN) , urinary ?1-microglobulin (?1-MG), urinary albumin, urinary immuno-globulin G, creatinine clearance (CCr), and fractional sodium clearance (FENa) . Results BUN, urinary albumin, urinary immuno-globulin G, CCr and FENa were normal during the study in both groups. Urinary concentration of ?1-MG was significantly increased at T2 as compared with the baseline value before anesthesia (T, ) and declined at T3 but was still significantly higher than that at T1 . There was no significant difference between the two groups in terms of the parameters mentioned above. Conclusion AHHD with 6% HES (200/0.5) has no detrimental effects on renal function in patients with normal function.
