Effect of tissue factor on intravascular migration of tumor cells
- VernacularTitle:组织因子在肿瘤细胞向血管内游走过程中的作用
- Author:
Hua XIN
;
Yajuan ZHENG
;
Zhenguo HAN
- Publication Type:Journal Article
- Keywords:
Thromboplastin;
Tumor cells;
Intravascular migration
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To evaluate the effect of tissue factor on intravascular migration of tumor cells.METHODS: Expression of tissue factor in tumor cells (HT1080) was analyzed by flow cytometry and immunofluorescence staining. An in vitro model was used to observe intravascular migration of tumor cells. RESULTS: High expression of tissue factor was observed in tumor cells (HT1080). The antibody for tissue factor inhibited intravascular migration of tumor cells. CONCLUSION: Tissue factor stimulated tumor metastasis through promoting intravascular migration of tumor cells.
