Effects of Jianwei Yuyang Granule on TGF-?_1 Expression during the Healing Process of Rat Gastric Ulcer Induced by Acetic Acid
- VernacularTitle:健胃愈疡颗粒剂对乙酸诱导的大鼠胃溃疡愈合过程中TGF-?1表达的影响
- Author:
Yongjie ZHOU
;
Jiabang LI
;
Shusheng LIAO
- Publication Type:Journal Article
- Keywords:
TGF-? 1;
Ulcer healing;
Jianwei Yuyang
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Jianwei Yuyang granule on TGF-? 1 expression in the healing process of rat gastric ulcer induced by acetic acid. Methods Animal model of gastric ulcer in rat was set up with the modified Okabe's method, and the TGF-? 1 expression in the gastric ulcerated tissues was detected by immunohistochemical technique. Results TGF-? 1 expression in gastric ulcerated tissues during the healing process in Jianwei Yuyang group significantly increased compared with the normal, model and famotidine treatment groups. Conclusion TGF-? 1 expression in gastric ulcerated tissues induced by acetic acid during the healing process significantly increased,especially in Jianwei Yuyang group. Jianwei Yuyang granule may accelerate gastric ulcer healing by increasing TGF-? 1 expression in gastric ulcerated tissues.
