A Case of Nonclassifiable Interstitial Pneumonia after Allogeneic Hematopoietic Stem Cell Transplantation .
10.4046/trd.2009.66.2.122
- Author:
Ki Hwan JUNG
1
;
Hwa Jung SUNG
;
Ju Han LEE
;
Joungho HAN
;
Chol SHIN
;
Hyung Joo PARK
;
Je Hyeong KIM
Author Information
1. Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea. chepraxis@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Hematopoietic stem cell transplantation;
Interstitial lung disease;
Pneumothorax
- MeSH:
Adolescent;
Female;
Hematopoietic Stem Cell Transplantation;
Hematopoietic Stem Cells;
Humans;
Lung Diseases;
Lung Diseases, Interstitial;
Pneumothorax;
Pulmonary Fibrosis;
Transplants
- From:Tuberculosis and Respiratory Diseases
2009;66(2):122-126
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Despite the improvements in supportive care, early and late hematopoietic stem cell transplantation-related complications still remain a significant cause of morbidity and mortality. Pulmonary complications occur in 40~60% of patients who undergo allogeneic hematopoietic stem cell transplantation. Late-onset noninfectious pulmonary complications can occur months and even years after transplantation. Interstital lung disease has also been reported to be a late post-transplant complication. Exposure to cytotoxic drugs and/or irradiation has been implicated as a cause of pulmonary toxicity including pulmonary fibrosis. We report a case of an 18-year-old female with non-classifiable interstitial pneumonia that manifested eight and a half years after allogeneic hematopoietic stem cell transplantation. The condition worsened rapidly and the patient eventually died.
