Characteristics of transient outward potassium current in repolarization 1 phase from the canine right ventricular mid-myocardial cells
- VernacularTitle:犬右心室M细胞复极1期瞬间外向钾电流特性的研究
- Author:
Peng ZHOU
;
Xinchun YANG
;
Cuilan LI
;
Xiulan LIU
;
Ying GAO
;
Lizhong WANG
;
Jing LUO
- Publication Type:Journal Article
- Keywords:
Electrophysiology;
Dogs;
Heart;
Potassium current
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To examine the electrophysiological characteristics of transient outward potassium current(Ito 1) in repolarization 1 phase from the canine right ventricular M cells. METHODS: By use of whole cell patch-clamp technique, we quantitatively researched the ionic intensity, density of Ito 1 and the notch magnitude of action potential in repolarization 1 phase. RESULTS: (1) The activating process of Ito 1 of canine right ventricular M cells presented evident voltage-dependency. Under the condition of 37℃, 5 000 ms, 0 mV and +70 mV, the average peak Ito 1 intensity of right ventricular M cell were (690?380) pA and ( 3 130? 1 910) pA, respectively (P
