Influence of normal conditioned medium of astrocytes on the damaged neurons of cerebral hypoxia and reoxygenation in vitro
- VernacularTitle:星形胶质细胞正常条件培养液对体外脑缺氧/复氧损伤神经元的影响
- Author:
Yuetao SONG
;
Yipeng TANG
;
Qingtao HONG
- Publication Type:Journal Article
- Keywords:
Astrocytes;
Neurons;
Hypoxia, brain;
Conditioned medium
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the nutritional role of the normal conditioned medium of astrocytes (NCMA) on the injured cerebral cortex neurons induced by cerebral hypoxia and reoxygenation in vitro. METHODS: The normal and damaged neurons induced by hypoxia and reoxygenation were cultured with normal conditioned medium of astrocytes (NCMA) after the cerebral cortical astrocytes and neurons of rats were isolated. The viability and survival rate of cultured neurons were investigated by MTT method. RESULTS: NCMA increased the viability and survival rate of cultured neurons. CONCLUSION: NCMA has nutritional and supporting roles on cultured neurons.
